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KMID : 1033620110380020093
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Clinical and Experimental Reproductive Medicine
2011 Volume.38 No. 2 p.93 ~ p.97
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Age specific serum anti-Mullerian hormone levels in 1,298 Korean women with regular menstruation
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Yoo Ji-Hee
Kim Hye-Ok
Cha Sun-Wha
Park Chan-Woo
Yang Kwang-Moon
Song In-Ok
Koong Mi-Kyoung
Kang Inn-Soo
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Abstract
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Objective: To determine the age specific serum anti-Mullerian hormone (AMH) reference values in Korean women with regular menstruation.
Methods: Between May, 2010 and January, 2011, the serum AMH levels were evaluated in a total of 1,298 women who have regular menstrual cycles aged between 20 and 50 years. Women were classified into 6 categories by age: 20-31 years, 32-34 years, 35-37 years, 38-40 years, 41-43 years, above 43 years. Measurement of serum AMH was measured by commercial enzyme-linked immunoassay.
Results: The serum AMH levels correlated negatively with age. The median AMH level of each age group was 4.20 ng/mL, 3.70 ng/mL, 2.60 ng/mL, 1.50 ng/mL, 1.30 ng/mL, and 0.60 ng/mL, respectively. The AMH values in the lower 5th percentile of each age group were 1.19 ng/mL, 0.60 ng/mL, 0.42 ng/mL, 0.27 ng/mL, 0.14 ng/mL, and 0.10 ng/mL, respectively.
Conclusion: This study determined reference values of serum AMH in Korean women with regular menstruation. These values can be applied to clinical evaluation and treatment of infertile women.
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KEYWORD
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Anti-Mullerian Hormone, Ovarian Reserve, Korean, Human
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